Macrolane VRF 30 – 10ml

Macrolane® VRF 30 is a high-density stabilized hyaluronic acid (NASHA) injectable gel designed for large-volume body contouring and soft tissue augmentation. It was developed by Q-Med (now part of Galderma, Sweden) and used in aesthetic medicine as a non-surgical alternative for body shaping and volume restoration. It is intended only for administration by trained medical professionals, and it is no longer widely used today due to regulatory restrictions in several indications. Macrolane VRF 30 is the thicker, higher-support variant of the Macrolane system (compared to VRF 20). It provides a temporary implant-like effect without surgery.

Packaging

• 1 × 10 mL pre-filled syringe
• Sterile, single-use injectable gel
• NASHA stabilized hyaluronic acid technology

Composition

• Cross-linked hyaluronic acid (NASHA technology)
• Approximately 20–22 mg/mL HA concentration (typical range reported for Macrolane systems)
• Phosphate-buffered saline solution
• Highly purified, non-animal origin hyaluronic acid

Limitations / Safety Notes

• Withdrawn or restricted in many markets
• Not recommended for breast augmentation in many regions due to imaging interference issues (e.g., mammography distortion)
• Requires large injection volumes for noticeable results
• Temporary results (not permanent implant alternative)

Safety Information

Must only be used by qualified healthcare professionals.

Possible side effects:

• Swelling
• Bruising
• Pain at injection site
• Irregular contours
• Nodules or firmness

Rare risks:

• Infection
• Vascular complications
• Inflammatory reactions
• Imaging complications in breast tissue

Mechanism of Action

Macrolane VRF 30 works by:

• Occupying large subcutaneous spaces
• Binding water molecules to create volume expansion
• Providing temporary structural augmentation
• Integrating into soft tissue for contour shaping

Because it is more viscous than VRF 20, it provides:

• Stronger lift
• Greater projection
• More structural support for deeper areas

Product Features

• High-density NASHA hyaluronic acid gel
• Designed for deep tissue volumization
• Strong lifting and shaping capability
• Minimally invasive alternative to implants
• Temporary effect (biodegradable HA implant)
• Outpatient injectable procedure

Expected Results

• Immediate and visible volume increase
• Improved body contour symmetry
• Smoother surface irregularities
• Natural-looking soft tissue enhancement

Duration typically reported:

• ~12–18 months depending on area and metabolism

Advantages

• Non-surgical body shaping option
• No donor fat required
• Adjustable and reversible compared to permanent implants
• Predictable volumizing effect
• Biodegradable hyaluronic acid material

Common Treatment Areas (Historical Use)

Macrolane VRF 30 was used for:

• Body contour enhancement
• Buttock augmentation
• Calf shaping
• Correction of post-liposuction depressions
• Soft tissue asymmetries
• Breast augmentation (later restricted)

It was applied in deep subcutaneous layers for maximum volume effect.