Masport 500 IU

Masport® 500 Units is a prescription botulinum toxin type A injectable developed by MasoonDarou Pharmaceutical Co. (Iran). It is supplied as a sterile, lyophilized (freeze-dried) powder for reconstitution before injection and is intended for both aesthetic and therapeutic applications. Masport has been used clinically for over a decade and is available in 150, 300, and 500 Unit presentations. Masport should be administered only by qualified healthcare professionals trained in botulinum toxin injection techniques. Masport 500 Units contains botulinum toxin type A, which temporarily relaxes targeted muscles by blocking the release of acetylcholine at the neuromuscular junction. This helps reduce the appearance of dynamic facial wrinkles and is also used in selected therapeutic conditions involving muscle overactivity.

Packaging

• 1 sterile vial containing 500 Units of botulinum toxin type A
• Lyophilized (freeze-dried) powder for injection
• Single-use vial
• Requires reconstitution with preservative-free sterile 0.9% sodium chloride solution before administration.

Composition

Each vial contains:

• Botulinum toxin type A: 500 Units

The formulation is supplied as a sterile lyophilized powder. Exact inactive ingredients may vary slightly by market and manufacturer.

Safety Information

Masport should only be administered by qualified healthcare professionals.

Possible side effects include:

• Injection-site pain
• Redness
• Swelling
• Bruising
• Headache
• Temporary muscle weakness near the injection site

Rare but serious risks include:

• Eyelid or eyebrow drooping (ptosis)
• Difficulty swallowing or speaking
• Allergic reactions
• Spread of toxin effects beyond the injection site

Contraindications:

• Hypersensitivity to botulinum toxin type A or any formulation component
• Infection at the proposed injection site
• Certain neuromuscular disorders (such as myasthenia gravis or Lambert-Eaton syndrome)
• Pregnancy or breastfeeding unless recommended by a healthcare provider.

Key Characteristics

• High-purity botulinum toxin type A
• Sterile, freeze-dried formulation
• Manufactured under current Good Manufacturing Practice (cGMP) standards
• Designed for professional medical use only.

Mechanism of Action

Masport works by:

• Blocking acetylcholine release at the neuromuscular junction
• Preventing temporary muscle contraction
• Relaxing targeted muscles
• Softening dynamic facial wrinkles
• Reducing excessive muscle activity in treated areas

Muscle function gradually returns as new nerve endings regenerate over time.

Product Features

• 500 Units of botulinum toxin type A per vial
• High-purity formulation
• Sterile lyophilized powder
• Temporary muscle relaxation
• Suitable for aesthetic and therapeutic applications
• Available in multiple vial strengths (150 U, 300 U, and 500 U)
• Store refrigerated at 2°C–8°C before reconstitution.

Expected Results

Typical outcomes include:

• Smoother forehead and frown lines
• Reduced crow’s feet
• Improved facial symmetry
• Reduction in excessive sweating
• Relief from selected muscle disorders

Initial effects are generally noticeable within 2–7 days, with peak results seen in 1–2 weeks. Results typically last 3–6 months, depending on the treatment area, dosage, and individual patient response. Clinical studies have demonstrated efficacy comparable to Dysport® for the treatment of glabellar lines.

Advantages

• High-purity botulinum toxin type A
• Clinically validated safety and efficacy
• Long-lasting yet temporary results
• Suitable for multiple cosmetic and therapeutic indications
• Reliable performance with proper administration
• Widely used in professional aesthetic practice.

Common Treatment Areas

A qualified healthcare professional may use Masport for:

• Forehead lines
• Glabellar (frown) lines
• Crow’s feet
• Bunny lines
• Chin dimpling
• Jawline (masseter hypertrophy)
• Neck bands
• Underarm and palm hyperhidrosis
• Selected neuromuscular disorders